Munn occasionally worked as an actress in the late 2000s as well, appearing in a lead role on the television series Beyond the Break from 2006 to 2009, as well in supporting parts in the comedy films Big Stan (2007) and Date Night (2010), the superhero film Iron Man 2 (2010), and Steven Soderbergh‘s comedy Magic Mike (2012).
In 2012, Munn was cast as Sloan Sabbith in Aaron Sorkin‘s HBO political drama series The Newsroom, and appeared on the series for all three seasons. She subsequently starred in the supernatural horror film Deliver Us from Evil (2014), the comedy Mortdecai (2015), and X-Men: Apocalypse (2016) as Psylocke. In 2017, she provided the voice of Koko in The Lego Ninjago Movie, and also had a lead role on the History Channel series Six (2017). In 2018, she had a leading role in the science fiction film The Predator, the fourth film in the Predator franchise.